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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN1
All Species:
1.52
Human Site:
S603
Identified Species:
2.56
UniProt:
Q16512
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16512
NP_002732.3
942
103932
S603
T
P
G
P
A
L
C
S
P
L
R
K
S
P
L
Chimpanzee
Pan troglodytes
XP_512443
1169
127241
Q830
T
P
G
P
A
P
V
Q
P
S
E
E
V
T
L
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
G655
M
E
P
R
T
R
R
G
P
S
P
P
A
S
P
Dog
Lupus familis
XP_542019
1076
118222
S736
E
T
P
G
P
A
L
S
S
P
L
K
K
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P70268
946
104392
C606
E
T
P
G
P
G
L
C
S
P
L
R
K
S
P
Rat
Rattus norvegicus
Q63433
946
104449
C606
E
T
P
G
P
G
L
C
S
P
L
R
K
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
H643
G
S
N
S
R
G
S
H
R
A
G
Q
I
P
T
Chicken
Gallus gallus
XP_422357
1013
114806
A627
M
K
A
P
D
M
P
A
Q
D
D
V
S
T
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689331
948
107057
K612
H
S
L
S
S
K
Q
K
K
T
S
L
S
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
Y329
K
K
G
T
D
E
I
Y
A
I
K
V
L
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
E402
A
E
R
K
G
T
D
E
V
Y
A
I
K
I
L
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
D463
Q
E
I
S
A
M
D
D
G
T
L
M
T
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
H788
S
L
A
P
T
S
T
H
P
S
R
T
T
D
Q
Red Bread Mold
Neurospora crassa
P87253
1142
127954
P761
Q
T
P
Q
Q
V
S
P
M
Y
Q
Q
N
P
Q
Conservation
Percent
Protein Identity:
100
79.3
38.7
83
N.A.
91.6
91.9
N.A.
42.2
57.6
N.A.
66.7
N.A.
29
N.A.
27.8
48.5
Protein Similarity:
100
79.9
52.6
84.3
N.A.
94.7
94.6
N.A.
56.1
72.1
N.A.
79.5
N.A.
42.8
N.A.
43.4
61.7
P-Site Identity:
100
46.6
6.6
13.3
N.A.
0
0
N.A.
6.6
13.3
N.A.
6.6
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
53.3
13.3
13.3
N.A.
6.6
6.6
N.A.
13.3
26.6
N.A.
13.3
N.A.
20
N.A.
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
28.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.4
45.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
0
22
8
0
8
8
8
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
8
15
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
15
0
15
8
0
8
8
0
0
8
0
% D
% Glu:
22
22
0
0
0
8
0
8
0
0
8
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
0
22
22
8
22
0
8
8
0
8
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
0
0
8
0
8
8
8
0
% I
% Lys:
8
15
0
8
0
8
0
8
8
0
8
15
29
8
8
% K
% Leu:
0
8
8
0
0
8
22
0
0
8
29
8
8
15
22
% L
% Met:
15
0
0
0
0
15
0
0
8
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
15
36
29
22
8
8
8
29
22
8
8
0
22
29
% P
% Gln:
15
0
0
8
8
0
8
8
8
0
8
15
0
0
22
% Q
% Arg:
0
0
8
8
8
8
8
0
8
0
15
15
0
0
0
% R
% Ser:
8
15
0
22
8
8
15
15
22
22
8
0
22
29
0
% S
% Thr:
15
29
0
8
15
8
8
0
0
15
0
8
15
15
8
% T
% Val:
0
0
0
0
0
8
8
0
8
0
0
15
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
15
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _